Blood in the stool occurs in almost everyone with the disease. The presenting symptoms of ulcerative proctitis all relate to the rectum. Progression of this disease to ulcerative colitis, extending farther up the bowel to involve the sigmoid colon, occurs in about 30-50% of those with ulcerative proctitis. A diagnosis of ulcerative proctitis can occur at any point throughout life, with a high occurrence in young children and then again around 40-50 years of age. There is a slightly increased risk for those who have a family member with the condition.Īlthough there is a range of treatments to help ease symptoms and induce remission, there is no cure. It is unclear why the inflammation is limited to the rectum.
The cause of ulcerative proctitis is undetermined but there is considerable research evidence to suggest that interactions between environmental factors, intestinal flora, immune dysregulation, and genetic predisposition are responsible. About 25-30% of those diagnosed with ulcerative colitis might actually have ulcerative proctitis. In this form of colitis, the inflammation begins at the rectum, and spreads no more than about 20 cm (7-8″) into the colon.
Ulcerative proctitis is a mild form of ulcerative colitis, a chronic inflammatory bowel disease (IBD) consisting of fine ulcerations in the inner mucosal lining of the large intestine that do not penetrate the bowel muscle wall. Click here to download a PDF of this information.
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